Systematic analysis of circulating soluble angiogenesis-associated proteins in ICON7 identifies Tie2 as a biomarker of vascular progression on bevacizumab

BACKGROUND: There is a critical need for predictive/resistance biomarkers for VEGF inhibitors to optimise their use. METHODS: Blood samples were collected during and following treatment and, where appropriate, upon progression from ovarian cancer patients in ICON7, a randomised phase III trial of ca...

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Bibliografski detalji
Izdano u:Br J Cancer
Glavni autori: Zhou, Cong, Clamp, Andrew, Backen, Alison, Berzuini, Carlo, Renehan, Andrew, Banks, Rosamonde E, Kaplan, Richard, Scherer, Stefan J, Kristensen, Gunnar B, Pujade-Lauraine, Eric, Dive, Caroline, Jayson, Gordon C
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Molecular Diagnostics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947705/
https://ncbi.nlm.nih.gov/pubmed/27351218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.194
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