WW domain binding protein 5 induces multidrug resistance of small cell lung cancer under the regulation of miR-335 through the Hippo pathway

BACKGROUND: Our previous study indicated that WW domain binding protein 5 (WBP5) expression was elevated significantly in a drug-resistant cell compared with its parental cell. Nevertheless, its functional role and underlying mechanisms remain unknown. METHODS: In this study, WBP5 was examined in 62...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Tang, Ruixiang, Lei, Yingying, Hu, Bingshuang, Yang, Jie, Fang, Shun, Wang, Qiongyao, Li, Man, Guo, Linlang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947702/
https://ncbi.nlm.nih.gov/pubmed/27336605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.186
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