Quantitative In Vitro and In Vivo Evaluation of Intestinal and Blood-Brain Barrier Transport Kinetics of the Plant N-Alkylamide Pellitorine

Objective. To evaluate the gut mucosa and blood-brain barrier (BBB) pharmacokinetic permeability properties of the plant N-alkylamide pellitorine. Methods. Pure pellitorine and an Anacyclus pyrethrum extract were used to investigate the permeation of pellitorine through (1) a Caco-2 cell monolayer,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biomed Res Int
Egile Nagusiak: Veryser, Lieselotte, Bracke, Nathalie, Wynendaele, Evelien, Joshi, Tanmayee, Tatke, Pratima, Taevernier, Lien, De Spiegeleer, Bart
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947679/
https://ncbi.nlm.nih.gov/pubmed/27493960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5497402
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