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Dynamic deformability of sickle red blood cells in microphysiological flow
In sickle cell disease (SCD), hemoglobin molecules polymerize intracellularly and lead to a cascade of events resulting in decreased deformability and increased adhesion of red blood cells (RBCs). Decreased deformability and increased adhesion of sickle RBCs lead to blood vessel occlusion (vaso-occl...
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Publicado no: | Technology (Singap World Sci) |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4947547/ https://ncbi.nlm.nih.gov/pubmed/27437432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S2339547816400045 |
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