Differential frequency of NKG2C/KLRC2 deletion in distinct African populations and susceptibility to Trachoma: a new method for imputation of KLRC2 genotypes from SNP genotyping data

NKG2C is an activating receptor that is preferentially expressed on natural killer (NK) cells. The gene encoding NKG2C (killer cell lectin-like receptor C2, KLRC2) is present at different copy numbers in the genomes of different individuals. Deletion at the NKG2C locus was investigated in a case–con...

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Veröffentlicht in:Hum Genet
Hauptverfasser: Goncalves, Adriana, Makalo, Pateh, Joof, Hassan, Burr, Sarah, Ramadhani, Athumani, Massae, Patrick, Malisa, Aiweda, Mtuy, Tara, Derrick, Tamsyn, Last, Anna R., Nabicassa, Meno, Cassama, Eunice, Houghton, Joanna, Palmer, Christine D., Pickering, Harry, Burton, Matthew J., Mabey, David C. W., Bailey, Robin L., Goodier, Martin R., Holland, Martin J., Roberts, Chrissy h.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2016
Schlagworte:
Original Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947484/
https://ncbi.nlm.nih.gov/pubmed/27312142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1694-2
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