Soluble guanylyl cyclase-activated cyclic GMP-dependent protein kinase inhibits arterial smooth muscle cell migration independent of VASP-Serine 239 phosphorylation

Coronary artery disease (CAD) accounts for over half of all cardiovascular disease-related deaths. Uncontrolled arterial smooth muscle (ASM) cell migration is a major component of CAD pathogenesis and efforts aimed at attenuating its progression are clinically essential. Cyclic nucleotide signaling...

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Udgivet i:Cell Signal
Main Authors: Holt, Andrew W., Martin, Danielle N., Shaver, Patti R., Adderley, Shaquria P., Stone, Joshua D., Joshi, Chintamani N., Francisco, Jake T., Lust, Robert M., Weidner, Douglas A., Shewchuk, Brian M., Tulis, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947434/
https://ncbi.nlm.nih.gov/pubmed/27302407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.06.012
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