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High levels of antibody that neutralize B-cell infection of Epstein-Barr virus and that bind EBV gp350 are associated with a lower risk of nasopharyngeal carcinoma

BACKGROUND: Elevated IgA antibodies indicative of ongoing exposure to Epstein Barr virus (EBV) are high-risk biomarkers for nasopharyngeal carcinoma (NPC), an EBV-related epithelial tumor. However, protective biomarkers that limit exposure to the virus have not been defined. We evaluated whether ant...

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Publicat a:Clin Cancer Res
Autors principals: Coghill, Anna E., Bu, Wei, Nguyen, Hanh, Hsu, Wan-Lun, Yu, Kelly J., Lou, Pei-Jen, Wang, Cheng-Ping, Chen, Chien-Jen, Hildesheim, Allan, Cohen, Jeffrey I.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947430/
https://ncbi.nlm.nih.gov/pubmed/26920891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2299
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