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Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy

B7-H3 (CD276) is an important immune checkpoint member of the B7 and CD28 families. Induced on antigen presenting cells, B7-H3 plays an important role in the inhibition of T cell function. Importantly, B7-H3 is highly overexpressed on a wide range of human solid cancers and often correlates with bot...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Picarda, Elodie, Ohaegbulam, Kim C., Zang, Xingxing
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947428/
https://ncbi.nlm.nih.gov/pubmed/27208063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2428
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