Phase III Double-Blind, Placebo-Controlled, Prospective Randomized Trial of Adjuvant Tamoxifen vs. Tamoxifen and Fenretinide in Postmenopausal Women with Positive Receptors (EB193): An Intergroup Trial Coordinated by the Eastern Cooperative Oncology Group

PURPOSE: Fenretinide and tamoxifen have additive antitumor effects preclinically. We performed a randomized, placebo-controlled, double-blind adjuvant trial in breast cancer patients treated for five years with tamoxifen, with or without fenretinide. PATIENTS AND METHODS: Between October 1995 and Oc...

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Detalhes bibliográficos
Publicado no:Med Oncol
Main Authors: Rao, Ruta D., Cobleigh, Melody A., Gray, Robert, Graham, Mark L., Norton, Larry, Martino, Silvana, Budd, George Thomas, Ingle, James N., Wood, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947231/
https://ncbi.nlm.nih.gov/pubmed/20878269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12032-010-9682-1
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