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Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity

Neurons display a highly polarized microtubule network that mediates trafficking throughout the extensive cytoplasm and is crucial for neuronal differentiation and function. In newborn migrating neurons, the microtubule network is organized by the centrosome. During neuron maturation, however, the c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sánchez-Huertas, Carlos, Freixo, Francisco, Viais, Ricardo, Lacasa, Cristina, Soriano, Eduardo, Lüders, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947180/
https://ncbi.nlm.nih.gov/pubmed/27405868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12187
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