Fluorescence imaging of ATP in neutrophils from patients with sepsis using organelle-localizable fluorescent chemosensors

BACKGROUND: The activation of polymorphonuclear neutrophils (PMNs) plays an important role in sepsis. Previously, we showed that ATP release and feedback via ATP receptors are essential for PMN activation; however, the dynamics remain poorly understood. Two new fluorescent chemosensors, PMAP-1 and M...

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Detalhes bibliográficos
Publicado no:Ann Intensive Care
Main Authors: Sueyoshi, Koichiro, Sumi, Yuka, Inoue, Yoshiaki, Kuroda, Yoko, Ishii, Kumiko, Nakayama, Hitoshi, Iwabuchi, Kazuhisa, Kurishita, Yasutaka, Shigemitsu, Hajime, Hamachi, Itaru, Tanaka, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Paris 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947066/
https://ncbi.nlm.nih.gov/pubmed/27422255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13613-016-0175-z
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