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A Powerful Mitochondria-Targeted Iron Chelator Affords High Photoprotection against Solar Ultraviolet A Radiation

Mitochondria are the principal destination for labile iron, making these organelles particularly susceptible to oxidative damage on exposure to ultraviolet A (UVA, 320–400 nm), the oxidizing component of sunlight. The labile iron-mediated oxidative damage caused by UVA to mitochondria leads to necro...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Reelfs, Olivier, Abbate, Vincenzo, Hider, Robert C., Pourzand, Charareh
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946793/
https://ncbi.nlm.nih.gov/pubmed/27109868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.03.041
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