Utility of KRAS mutation detection using circulating cell‐free DNA from patients with colorectal cancer

In this study, we evaluated the clinical utility of detecting KRAS mutations in circulating cell‐free (ccf)DNA of metastatic colorectal cancer patients. We prospectively recruited 94 metastatic colorectal cancer patients. Circulating cell‐free DNA was extracted from plasma samples and analyzed for t...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Yamada, Takeshi, Iwai, Takuma, Takahashi, Goro, Kan, Hayato, Koizumi, Michihiro, Matsuda, Akihisa, Shinji, Seiichi, Yamagishi, Aya, Yokoyama, Yasuyuki, Tatsuguchi, Atsushi, Kawagoe, Tatsuro, Kitano, Shiro, Nakayama, Masato, Matsumoto, Satoshi, Uchida, Eiji
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946708/
https://ncbi.nlm.nih.gov/pubmed/27116474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12959
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