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Analyzing the potential for incorrect haplotype calls with different pharmacogenomic assays in different populations: a simulation based on 1000 Genomes data

AIM: Many currently available pharmacogenomic assays and algorithms interrogate a set of ‘tag’ polymorphisms for inferring haplotypes. We wanted to test the accuracy of such haplotype inferences across different populations. MATERIALS & METHODS: We simulated haplotype inferences made by existing...

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Détails bibliographiques
Publié dans:Pharmacogenomics
Auteurs principaux: Samwald, Matthias, Blagec, Kathrin, Hofer, Sebastian, Freimuth, Robert R
Format: Artigo
Langue:Inglês
Publié: Future Medicine Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946345/
https://ncbi.nlm.nih.gov/pubmed/26419264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.15.108
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