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Bile acids destabilise HIF-1α and promote anti-tumour phenotypes in cancer cell models

BACKGROUND: The role of the microbiome has become synonymous with human health and disease. Bile acids, as essential components of the microbiome, have gained sustained credibility as potential modulators of cancer progression in several disease models. At physiological concentrations, bile acids ap...

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Publicado en:BMC Cancer
Autores principales: Phelan, J. P., Reen, F. J., Dunphy, N., O’Connor, R., O’Gara, F.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946243/
https://ncbi.nlm.nih.gov/pubmed/27416726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2528-2
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