Lymphocytes influence intracranial aneurysm formation and rupture: role of extracellular matrix remodeling and phenotypic modulation of vascular smooth muscle cells

BACKGROUND: Intracranial aneurysms (IA) are increasingly recognized as a disease driven by chronic inflammation. Recent research has identified key mediators and processes underlying IA pathogenesis, but mechanistic understanding remains incomplete. Lymphocytic infiltrates have been demonstrated in...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Sawyer, David M., Pace, Lauren A., Pascale, Crissey L., Kutchin, Alexander C., O’Neill, Brannan E., Starke, Robert M., Dumont, Aaron S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946206/
https://ncbi.nlm.nih.gov/pubmed/27416931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0654-z
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