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Noise processing by microRNA-mediated circuits: The Incoherent Feed-Forward Loop, revisited

The intrinsic stochasticity of gene expression is usually mitigated in higher eukaryotes by post-transcriptional regulation channels that stabilise the output layer, most notably protein levels. The discovery of small non-coding RNAs (miRNAs) in specific motifs of the genetic regulatory network has...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Heliyon
Hauptverfasser: Grigolon, Silvia, Di Patti, Francesca, De Martino, Andrea, Marinari, Enzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946084/
https://ncbi.nlm.nih.gov/pubmed/27441269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2016.e00095
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