Common Variation in the DOPA Decarboxylase (DDC) Gene and Human Striatal DDC Activity In Vivo

The synthesis of multiple amine neurotransmitters, such as dopamine, norepinephrine, serotonin, and trace amines, relies in part on DOPA decarboxylase (DDC, AADC), an enzyme that is required for normative neural operations. Because rare, loss-of-function mutations in the DDC gene result in severe en...

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Publicado en:Neuropsychopharmacology
Autores principales: Eisenberg, Daniel P, Kohn, Philip D, Hegarty, Catherine E, Ianni, Angela M, Kolachana, Bhaskar, Gregory, Michael D, Masdeu, Joseph C, Berman, Karen F
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946061/
https://ncbi.nlm.nih.gov/pubmed/26924680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.31
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