Common Variation in the DOPA Decarboxylase (DDC) Gene and Human Striatal DDC Activity In Vivo

The synthesis of multiple amine neurotransmitters, such as dopamine, norepinephrine, serotonin, and trace amines, relies in part on DOPA decarboxylase (DDC, AADC), an enzyme that is required for normative neural operations. Because rare, loss-of-function mutations in the DDC gene result in severe en...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Eisenberg, Daniel P, Kohn, Philip D, Hegarty, Catherine E, Ianni, Angela M, Kolachana, Bhaskar, Gregory, Michael D, Masdeu, Joseph C, Berman, Karen F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946061/
https://ncbi.nlm.nih.gov/pubmed/26924680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.31
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