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Tetraspanin CD82 Regulates the Spatiotemporal Dynamics of PKCα in Acute Myeloid Leukemia

Patients with acute myeloid leukemia (AML) have increased myeloid cells within their bone marrow that exhibit aberrant signaling. Therefore, therapeutic targets that modulate disrupted signaling cascades are of significant interest. In this study, we demonstrate that the tetraspanin membrane scaffol...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Termini, Christina M., Lidke, Keith A., Gillette, Jennifer M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945921/
https://ncbi.nlm.nih.gov/pubmed/27417454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29859
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