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Copy number variation of E3 ubiquitin ligase genes in peripheral blood leukocyte and colorectal cancer

Given that E3 ubiquitin ligases (E3) regulate specific protein degradation in many cancer-related biological processes. E3 copy number variation (CNV) may affect the development and prognosis of colorectal cancer (CRC). Therefore, we detected CNVs of five E3 genes in 518 CRC patients and 518 age, ge...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bi, Haoran, Tian, Tian, Zhu, Lin, Zhou, Haibo, Hu, Hanqing, Liu, Yanhong, Li, Xia, Hu, Fulan, Zhao, Yashuang, Wang, Guiyu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945909/
https://ncbi.nlm.nih.gov/pubmed/27417709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29869
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