The L‐type Ca(2+) channel facilitates abnormal metabolic activity in the cTnI‐G203S mouse model of hypertrophic cardiomyopathy

KEY POINTS: Genetic mutations in cardiac troponin I (cTnI) are associated with development of hypertrophic cardiomyopathy characterized by myocyte remodelling, disorganization of cytoskeletal proteins and altered energy metabolism. The L‐type Ca(2+) channel is the main route for calcium influx and i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Physiol
Päätekijät: Viola, Helena, Johnstone, Victoria, Cserne Szappanos, Henrietta, Richman, Tara, Tsoutsman, Tatiana, Filipovska, Aleksandra, Semsarian, Christopher, Hool, Livia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Cardiovascular
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945708/
https://ncbi.nlm.nih.gov/pubmed/27062056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271681
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia