The L‐type Ca(2+) channel facilitates abnormal metabolic activity in the cTnI‐G203S mouse model of hypertrophic cardiomyopathy

KEY POINTS: Genetic mutations in cardiac troponin I (cTnI) are associated with development of hypertrophic cardiomyopathy characterized by myocyte remodelling, disorganization of cytoskeletal proteins and altered energy metabolism. The L‐type Ca(2+) channel is the main route for calcium influx and i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Physiol
Prif Awduron: Viola, Helena, Johnstone, Victoria, Cserne Szappanos, Henrietta, Richman, Tara, Tsoutsman, Tatiana, Filipovska, Aleksandra, Semsarian, Christopher, Hool, Livia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Cardiovascular
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945708/
https://ncbi.nlm.nih.gov/pubmed/27062056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271681
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg