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The L‐type Ca(2+) channel facilitates abnormal metabolic activity in the cTnI‐G203S mouse model of hypertrophic cardiomyopathy
KEY POINTS: Genetic mutations in cardiac troponin I (cTnI) are associated with development of hypertrophic cardiomyopathy characterized by myocyte remodelling, disorganization of cytoskeletal proteins and altered energy metabolism. The L‐type Ca(2+) channel is the main route for calcium influx and i...
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| Publicado en: | J Physiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945708/ https://ncbi.nlm.nih.gov/pubmed/27062056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271681 |
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