The L‐type Ca(2+) channel facilitates abnormal metabolic activity in the cTnI‐G203S mouse model of hypertrophic cardiomyopathy

KEY POINTS: Genetic mutations in cardiac troponin I (cTnI) are associated with development of hypertrophic cardiomyopathy characterized by myocyte remodelling, disorganization of cytoskeletal proteins and altered energy metabolism. The L‐type Ca(2+) channel is the main route for calcium influx and i...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Physiol
Main Authors: Viola, Helena, Johnstone, Victoria, Cserne Szappanos, Henrietta, Richman, Tara, Tsoutsman, Tatiana, Filipovska, Aleksandra, Semsarian, Christopher, Hool, Livia
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Cardiovascular
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945708/
https://ncbi.nlm.nih.gov/pubmed/27062056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271681
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla