Preparation and clinical evaluation of a novel lozenge containing polaprezinc, a zinc-L-carnosine, for prevention of oral mucositis in patients with hematological cancer who received high-dose chemotherapy

We previously reported that oral ingestion of polaprezinc, a zinc-L-carnosine, suspended in sodium alginate solution prevents oral mucositis in patients receiving radiotherapy or high-dose chemotherapy. In the present study, we developed a novel preparation of polaprezinc and evaluated clinical effe...

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Veröffentlicht in:Med Oncol
Hauptverfasser: Hayashi, Hiroko, Kobayashi, Ryo, Suzuki, Akio, Yamada, Yuto, Ishida, Masayuki, Shakui, Toshinobu, Kitagawa, Junichi, Hayashi, Hideki, Sugiyama, Tadashi, Takeuchi, Hirofumi, Tsurumi, Hisashi, Itoh, Yoshinori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2016
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945687/
https://ncbi.nlm.nih.gov/pubmed/27418192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12032-016-0795-z
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