Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 Family

Reprogramming to pluripotency after overexpression of OCT4, SOX2, KLF4, and MYC is accompanied by global genomic and epigenomic changes. Histone modification and DNA methylation states in induced pluripotent stem cells (iPSCs) have been shown to be highly similar to embryonic stem cells (ESCs). Howe...

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Publicado no:Stem Cell Reports
Main Authors: Hysolli, Eriona, Tanaka, Yoshiaki, Su, Juan, Kim, Kun-Yong, Zhong, Tianyu, Janknecht, Ralf, Zhou, Xiao-Ling, Geng, Lin, Qiu, Caihong, Pan, Xinghua, Jung, Yong-Wook, Cheng, Jijun, Lu, Jun, Zhong, Mei, Weissman, Sherman M., Park, In-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945581/
https://ncbi.nlm.nih.gov/pubmed/27373925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.05.014
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