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URINARY MITOCHONDRIAL-DNA COPY NUMBER IDENTIFIES CHRONIC RENAL INJURY IN HYPERTENSIVE PATIENTS

Mitochondrial injury contributes to renal dysfunction in several models of renal disease, but its involvement in human hypertension remains unknown. Fragments of the mitochondrial genome released from dying cells are considered surrogate markers of mitochondrial injury. We hypothesized that hyperten...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Eirin, Alfonso, Saad, Ahmed, Tang, Hui, Herrmann, Sandra M., Woollard, John R., Lerman², Amir, Textor, Stephen C., Lerman, Lilach O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945445/
https://ncbi.nlm.nih.gov/pubmed/27324229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07849
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