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Phasic Burst Stimulation: A Closed-Loop Approach to Tuning Deep Brain Stimulation Parameters for Parkinson’s Disease

We propose a novel, closed-loop approach to tuning deep brain stimulation (DBS) for Parkinson’s disease (PD). The approach, termed Phasic Burst Stimulation (PhaBS), applies a burst of stimulus pulses over a range of phases predicted to disrupt pathological oscillations seen in PD. Stimulation parame...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Holt, Abbey B., Wilson, Dan, Shinn, Max, Moehlis, Jeff, Netoff, Theoden I.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945037/
https://ncbi.nlm.nih.gov/pubmed/27415832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005011
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