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Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy

OBJECTIVE: Mucosal-associated invariant T (MAIT) cells comprise a subpopulation of T cells that can be activated by bacterial products and cytokines to produce IFN-γ. Since little is known on MAIT cells during HCV infection, we compared their phenotype and function in comparison to HIV and HCV/HIV c...

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Pubblicato in:PLoS One
Autori principali: Spaan, Michelle, Hullegie, Sebastiaan J., Beudeker, Boris J. B., Kreefft, Kim, van Oord, Gertine W., Groothuismink, Zwier M. A., van Tilborg, Marjolein, Rijnders, Bart, de Knegt, Robert J., Claassen, Mark A. A., Boonstra, Andre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945024/
https://ncbi.nlm.nih.gov/pubmed/27416100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159243
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