Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy

OBJECTIVE: Mucosal-associated invariant T (MAIT) cells comprise a subpopulation of T cells that can be activated by bacterial products and cytokines to produce IFN-γ. Since little is known on MAIT cells during HCV infection, we compared their phenotype and function in comparison to HIV and HCV/HIV c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Spaan, Michelle, Hullegie, Sebastiaan J., Beudeker, Boris J. B., Kreefft, Kim, van Oord, Gertine W., Groothuismink, Zwier M. A., van Tilborg, Marjolein, Rijnders, Bart, de Knegt, Robert J., Claassen, Mark A. A., Boonstra, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945024/
https://ncbi.nlm.nih.gov/pubmed/27416100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159243
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