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Nicotinamide Promotes Adipogenesis in Umbilical Cord-Derived Mesenchymal Stem Cells and Is Associated with Neonatal Adiposity: The Healthy Start BabyBUMP Project

The cellular mechanisms whereby excess maternal nutrition during pregnancy increases adiposity of the offspring are not well understood. However, nicotinamide (NAM), a fundamental micronutrient that is important in energy metabolism, has been shown to regulate adipogenesis through inhibition of SIRT...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shapiro, Allison L. B., Boyle, Kristen E., Dabelea, Dana, Patinkin, Zachary W., De la Houssaye, Becky, Ringham, Brandy M., Glueck, Deborah H., Barbour, Linda A., Norris, Jill M., Friedman, Jacob E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944979/
https://ncbi.nlm.nih.gov/pubmed/27414406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159575
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