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Dynamic changes of driver genes’ mutations across clinical stages in nine cancer types

The driver genes play critical roles for tumorigenesis, and the number of identified driver genes reached plateau. But how they act during different cancer development stages is lack of knowledge. We investigated 138 driver genes’ mutation changes across clinical stages using 3,477 cases in nine can...

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Detalhes bibliográficos
Publicado no:Cancer Med
Autor principal: Li, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944883/
https://ncbi.nlm.nih.gov/pubmed/26992457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.704
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