Nerve Growth Factor Gene Therapy Activates Neuronal Responses in Alzheimer’s Disease

IMPORTANCE: Alzheimer’s disease (AD) is the most common neurodegenerative disorder, and lacks effective disease modifying therapies. In 2001 we initiated a clinical trial of Nerve Growth Factor (NGF) gene therapy in AD, the first effort at gene delivery in an adult neurodegenerative disorder. This p...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Tuszynski, Mark H., Yang, Jennifer H., Barba, David, U, H S., Bakay, Roy, Pay, Mary M., Masliah, Eliezer, Conner, James M., Kobalka, Peter, Roy, Subhojit, Nagahara, Alan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944824/
https://ncbi.nlm.nih.gov/pubmed/26302439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2015.1807
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