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Dopamine D2 Receptor-Mediated Regulation of Pancreatic β Cell Mass
Understanding the molecular mechanisms that regulate β cell mass and proliferation is important for the treatment of diabetes. Here, we identified domperidone (DPD), a dopamine D2 receptor (DRD2) antagonist that enhances β cell mass. Over time, islet β cell loss occurs in dissociation cultures, and...
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| 發表在: | Stem Cell Reports |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4944721/ https://ncbi.nlm.nih.gov/pubmed/27373926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.05.015 |
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