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MiR-31/SDHA Axis Regulates Reprogramming Efficiency through Mitochondrial Metabolism
Metabolism is remodeled when somatic cells are reprogrammed into induced pluripotent stem cells (iPSCs), but the majority of iPSCs are not fully reprogrammed. In a shift essential for reprogramming, iPSCs use less mitochondrial respiration but increased anaerobic glycolysis for bioenergetics. We fou...
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| Publicado no: | Stem Cell Reports |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4944586/ https://ncbi.nlm.nih.gov/pubmed/27346679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.05.012 |
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