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SOX2 expression is associated with a cancer stem cell state and down-regulation of CDX2 in colorectal cancer

BACKGROUND: To improve current treatment strategies for patients with aggressive colorectal cancer (CRC), the molecular understanding of subgroups of CRC with poor prognosis is of vast importance. SOX2 positive tumors have been associated with a poor patient outcome, but the functional role of SOX2...

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Bibliografische gegevens
Gepubliceerd in:BMC Cancer
Hoofdauteurs: Lundberg, Ida V., Edin, Sofia, Eklöf, Vincy, Öberg, Åke, Palmqvist, Richard, Wikberg, Maria L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944515/
https://ncbi.nlm.nih.gov/pubmed/27411517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2509-5
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