Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.

We are developing efficient methods for gene transfer into tissue culture cells. We have previously shown that coupling of a chimeric adenovirus with polylysine allowed the construction of an adenovirus-polylysine-reporter-gene complex that transferred the transporter gene with great efficiency into...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wagner, E, Zatloukal, K, Cotten, M, Kirlappos, H, Mechtler, K, Curiel, D T, Birnstiel, M L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49445/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631096/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.13.6099
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