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Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.

We are developing efficient methods for gene transfer into tissue culture cells. We have previously shown that coupling of a chimeric adenovirus with polylysine allowed the construction of an adenovirus-polylysine-reporter-gene complex that transferred the transporter gene with great efficiency into...

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Autori principali: Wagner, E, Zatloukal, K, Cotten, M, Kirlappos, H, Mechtler, K, Curiel, D T, Birnstiel, M L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC49445/
https://ncbi.nlm.nih.gov/pubmed/1631096
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