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Avidity characterization of genetically engineered T-cells with novel and established approaches
BACKGROUND: Adoptive transfer of genetically engineered autologous T-cells is becoming a successful therapy for cancer. The avidity of the engineered T-cells is of crucial importance for therapy success. We have in the past cloned a T-cell receptor (TCR) that recognizes an HLA-A2 (MHC class I)-restr...
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| Publicado en: | BMC Immunol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4944473/ https://ncbi.nlm.nih.gov/pubmed/27411667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-016-0162-z |
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