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Unequal representation of genetic variation across ancestry groups creates healthcare inequality in the application of precision medicine

An important application of modern genomics is diagnosing genetic disorders. We use the largest publicly available exome sequence database to show that this key clinical service can currently be performed much more effectively in individuals of European genetic ancestry. ELECTRONIC SUPPLEMENTARY MAT...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Petrovski, Slavé, Goldstein, David B.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944427/
https://ncbi.nlm.nih.gov/pubmed/27418169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1016-y
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