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Understanding the structural mechanisms of antibiotic resistance sets the platform for new discovery

Understanding the structural basis of antibacterial resistance may enable rational design principles that avoid and subvert that resistance, thus leading to the discovery of more effective antibiotics. In this review, we explore the use of crystal structures to guide new discovery of antibiotics tha...

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Detalhes bibliográficos
Publicado no:Future Microbiol
Main Authors: Reeve, Stephanie M, Lombardo, Michael N, Anderson, Amy C
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944398/
https://ncbi.nlm.nih.gov/pubmed/26516790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb.15.78
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