Microbubbles and ultrasound increase intraventricular polyplex gene transfer to the brain

Neurons in the brain can be damaged or lost from neurodegenerative disease, stroke, or traumatic injury. Although neurogenesis occurs in mammalian adult brains, the levels of natural neurogenesis are insufficient to restore function in these cases. Gene therapy has been pursued as a promising strate...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Tan, James-Kevin Y., Pham, Binhan, Zong, Yujin, Perez, Camilo, Maris, Don O., Hemphill, Ashton, Miao, Carol, Matula, Thomas J., Mourad, Pierre D., Wei, Hua, Sellers, Drew L., Horner, Philip J., Pun, Suzie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944389/
https://ncbi.nlm.nih.gov/pubmed/26860281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.02.003
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