1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis

BACKGROUND: 1-methylnicotinamide (1-MNA), an endogenous metabolite of nicotinamide, has recently gained interest due to its anti-inflammatory and anti-thrombotic activities linked to the COX-2/PGI(2) pathway. Given the previously reported anti-metastatic activity of prostacyclin (PGI(2)), we aimed t...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Blazejczyk, Agnieszka, Switalska, Marta, Chlopicki, Stefan, Marcinek, Andrzej, Gebicki, Jerzy, Nowak, Marcin, Nasulewicz-Goldeman, Anna, Wietrzyk, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944260/
https://ncbi.nlm.nih.gov/pubmed/27412454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0389-9
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