TERT promoter mutations in pancreatic endocrine tumours are rare and mainly found in tumours from patients with hereditary syndromes

One of the hallmarks of cancer is its unlimited replicative potential that needs a compensatory mechanism for the consequential telomere erosion. Telomerase promoter (TERTp) mutations were recently reported as a novel mechanism for telomerase re-activation/expression in order to maintain telomere le...

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Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Vinagre, João, Nabais, Joana, Pinheiro, Jorge, Batista, Rui, Oliveira, Rui Caetano, Gonçalves, António Pedro, Pestana, Ana, Reis, Marta, Mesquita, Bárbara, Pinto, Vasco, Lyra, Joana, Cipriano, Maria Augusta, Ferreira, Miguel Godinho, Lopes, José Manuel, Sobrinho-Simões, Manuel, Soares, Paula
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944231/
https://ncbi.nlm.nih.gov/pubmed/27411289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29714
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