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Zwitterionic chitosan for the systemic treatment of sepsis

Severe sepsis and septic shock are life-threatening conditions, with Gram-negative organisms responsible for most sepsis mortality. Systemic administration of compounds that block the action of lipopolysaccharide (LPS), a constituent of the Gram-negative outer cell membrane, is hampered by their hyd...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Cho, Eun Jung, Doh, Kyung-Oh, Park, Jinho, Hyun, Hyesun, Wilson, Erin M., Snyder, Paul W., Tsifansky, Michael D., Yeo, Yoon
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944199/
https://ncbi.nlm.nih.gov/pubmed/27412050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29739
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