Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway

Annexin A1 (ANXA1) is a Ca(2+)-binding protein over-expressed in pancreatic cancer (PC). We recently reported that extracellular ANXA1 mediates PC cell motility acting on Formyl Peptide Receptors (FPRs). Here, we describe other mechanisms by which intracellular ANXA1 could mediate PC progression. We...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Belvedere, Raffaella, Bizzarro, Valentina, Forte, Giovanni, Dal Piaz, Fabrizio, Parente, Luca, Petrella, Antonello
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944142/
https://ncbi.nlm.nih.gov/pubmed/27412958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29660
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