Efficacy and Safety of Prucalopride in Chronic Constipation: An Integrated Analysis of Six Randomized, Controlled Clinical Trials

BACKGROUND: Prucalopride, a selective, high-affinity 5-hydroxytryptamine 4 receptor agonist, stimulates gastrointestinal and colonic motility and alleviates common symptoms of chronic constipation (CC) in adults. The relative efficacy by gender has not been evaluated. AIM: To evaluate the global eff...

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Detalhes bibliográficos
Publicado no:Dig Dis Sci
Main Authors: Camilleri, Michael, Piessevaux, Hubert, Yiannakou, Yan, Tack, Jan, Kerstens, René, Quigley, Eamonn M. M., Ke, MeiYun, Da Silva, Susana, Levine, Amy
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943977/
https://ncbi.nlm.nih.gov/pubmed/27056037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-016-4147-9
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