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Mimicking Metastases Including Tumor Stroma: A New Technique to Generate a Three-Dimensional Colorectal Cancer Model Based on a Biological Decellularized Intestinal Scaffold

Tumor models based on cancer cell lines cultured two-dimensionally (2D) on plastic lack histological complexity and functionality compared to the native microenvironment. Xenogenic mouse tumor models display higher complexity but often do not predict human drug responses accurately due to species-sp...

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Detalhes bibliográficos
Publicado no:Tissue Eng Part C Methods
Main Authors: Nietzer, Sarah, Baur, Florentin, Sieber, Stefan, Hansmann, Jan, Schwarz, Thomas, Stoffer, Carolin, Häfner, Heide, Gasser, Martin, Waaga-Gasser, Ana Maria, Walles, Heike, Dandekar, Gudrun
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943469/
https://ncbi.nlm.nih.gov/pubmed/27137941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tec.2015.0557
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