5‐Lipoxygenase Gene Variants Are Not Associated With Atherosclerosis or Incident Coronary Heart Disease in the Multi‐Ethnic Study of Atherosclerosis Cohort

BACKGROUND: The arachidonate 5‐lipoxygenase enzyme plays a crucial role in mediating inflammation to maintain homeostasis, yet certain allelic variants of the 5‐lipoxygenase gene, ALOX5, may increase risk of atherosclerosis and coronary heart disease (CHD). Further, relations between ALOX5 and disea...

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Dettagli Bibliografici
Pubblicato in:J Am Heart Assoc
Autori principali: Tsai, Michael Y., Cao, Jing, Steffen, Brian T., Weir, Natalie L., Rich, Stephen S., Liang, Shuang, Guan, Weihua
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943258/
https://ncbi.nlm.nih.gov/pubmed/27025886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002814
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