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Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus

BACKGROUND: Recent achievement in genetics and epigenetics has led to the exploration of the pathogenesis of systemic lupus erythematosus (SLE). Identification of differentially expressed genes and their regulatory mechanism(s) at whole-genome level will provide a comprehensive understanding of the...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Zhu, Honglin, Mi, Wentao, Luo, Hui, Chen, Tao, Liu, Shengxi, Raman, Indu, Zuo, Xiaoxia, Li, Quan-Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942934/
https://ncbi.nlm.nih.gov/pubmed/27412348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1050-x
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