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Novel cell-based in vitro screen to identify small-molecule inhibitors against intracellular replication of Cryptococcus neoformans in macrophages
The fungal pathogen Cryptococcus neoformans poses a major threat to immunocompromised patients and is a leading killer of human immunodeficiency virus (HIV)-infected patients worldwide. Cryptococci are known to manipulate host macrophages and can either remain latent or proliferate intracellularly w...
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Publicado no: | Int J Antimicrob Agents |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier Science Publishers
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942879/ https://ncbi.nlm.nih.gov/pubmed/27289450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2016.04.018 |
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