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Polymer physics of chromosome large-scale 3D organisation

Chromosomes have a complex architecture in the cell nucleus, which serves vital functional purposes, yet its structure and folding mechanisms remain still incompletely understood. Here we show that genome-wide chromatin architecture data, as mapped by Hi-C methods across mammalian cell types and chr...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Chiariello, Andrea M., Annunziatella, Carlo, Bianco, Simona, Esposito, Andrea, Nicodemi, Mario
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942835/
https://ncbi.nlm.nih.gov/pubmed/27405443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29775
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